PALM MicroBeam employs the LMPC method (Laser Microdissection and Pressure Catapulting) to extract biological material of interest out of a tissue specimen. The Zeiss P.A.L.M. system employs a UV laser pulsed microbeam to cut the desired material and the isolated tissue is then recovered by laser pressure catapult into a microfuge tube cap. Cutting accuracy of less than 1 µm can be achieved.
The source material can be placed on a normal objective glass slide or on a membrane slide, depending on the way of approaching. The system can be used with frozen or paraffin-embedded tissue samples, single cells, and even single chromosomes.
For more information:
http://microscopy.zeiss.com/microscopy/en_de/products/laser-microdissection/microbeam.html
Webinars:
http://www.zeiss.com/microscopy/en_de/products/laser-microdissection/microbeam.html – webinars